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Transcription factor target site search and gene regulation in a background of unspecific binding sites
Response time and transcription level are vital parameters of gene regulation. They depend on how fast transcription factors (TFs) find and how efficient they occupy their specific target sites. It is well known that target site search is accelerated by TF binding to and sliding along unspecific DNA...
Autores principales: | Hettich, J., Gebhardt, J.C.M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103292/ https://www.ncbi.nlm.nih.gov/pubmed/29870697 http://dx.doi.org/10.1016/j.jtbi.2018.05.037 |
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