Spindle Cell Carcinoma of the Lung/Pleura: An Incidental Finding

A 59-year-old male with a medical history of abdominal aortic dissection underwent a follow-up computed tomography (CT) scan abdomen, which showed an incidental pleural-based mass in the left lung base. The patient underwent an ultrasound (US)-guided biopsy and the histology was consistent with spin...

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Autores principales: Sardar, Muhammad, Azharuddin, Muhammad, Khan, Wahab J, Noory, Mohammad A, Shaikh, Nasreen, Malik, Saad Ullah, Du, Doantrang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2018
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103392/
https://www.ncbi.nlm.nih.gov/pubmed/30140599
http://dx.doi.org/10.7759/cureus.2848
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author Sardar, Muhammad
Azharuddin, Muhammad
Khan, Wahab J
Noory, Mohammad A
Shaikh, Nasreen
Malik, Saad Ullah
Du, Doantrang
author_facet Sardar, Muhammad
Azharuddin, Muhammad
Khan, Wahab J
Noory, Mohammad A
Shaikh, Nasreen
Malik, Saad Ullah
Du, Doantrang
author_sort Sardar, Muhammad
collection PubMed
description A 59-year-old male with a medical history of abdominal aortic dissection underwent a follow-up computed tomography (CT) scan abdomen, which showed an incidental pleural-based mass in the left lung base. The patient underwent an ultrasound (US)-guided biopsy and the histology was consistent with spindle cell carcinoma (SpCC). Staging workup was concerning for a metastatic lesion on the adrenal gland. The patient refused surgery and was subsequently started on chemotherapy. SpCC is a rare histological variant of sarcomatoid carcinoma. The prognosis is generally poor and treatment is the same as for other non-small cell lung cancers (NSCLC). The literature on disease progression and treatment is limited.
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spelling pubmed-61033922018-08-23 Spindle Cell Carcinoma of the Lung/Pleura: An Incidental Finding Sardar, Muhammad Azharuddin, Muhammad Khan, Wahab J Noory, Mohammad A Shaikh, Nasreen Malik, Saad Ullah Du, Doantrang Cureus Internal Medicine A 59-year-old male with a medical history of abdominal aortic dissection underwent a follow-up computed tomography (CT) scan abdomen, which showed an incidental pleural-based mass in the left lung base. The patient underwent an ultrasound (US)-guided biopsy and the histology was consistent with spindle cell carcinoma (SpCC). Staging workup was concerning for a metastatic lesion on the adrenal gland. The patient refused surgery and was subsequently started on chemotherapy. SpCC is a rare histological variant of sarcomatoid carcinoma. The prognosis is generally poor and treatment is the same as for other non-small cell lung cancers (NSCLC). The literature on disease progression and treatment is limited. Cureus 2018-06-20 /pmc/articles/PMC6103392/ /pubmed/30140599 http://dx.doi.org/10.7759/cureus.2848 Text en Copyright © 2018, Sardar et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Sardar, Muhammad
Azharuddin, Muhammad
Khan, Wahab J
Noory, Mohammad A
Shaikh, Nasreen
Malik, Saad Ullah
Du, Doantrang
Spindle Cell Carcinoma of the Lung/Pleura: An Incidental Finding
title Spindle Cell Carcinoma of the Lung/Pleura: An Incidental Finding
title_full Spindle Cell Carcinoma of the Lung/Pleura: An Incidental Finding
title_fullStr Spindle Cell Carcinoma of the Lung/Pleura: An Incidental Finding
title_full_unstemmed Spindle Cell Carcinoma of the Lung/Pleura: An Incidental Finding
title_short Spindle Cell Carcinoma of the Lung/Pleura: An Incidental Finding
title_sort spindle cell carcinoma of the lung/pleura: an incidental finding
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103392/
https://www.ncbi.nlm.nih.gov/pubmed/30140599
http://dx.doi.org/10.7759/cureus.2848
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