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Complement receptor 1 (CR1, CD35) association with susceptibility to leprosy

BACKGROUND: Pathophysiological mechanisms are still incompletely understood for leprosy, an urgent public health issue in Brazil. Complement receptor 1 (CR1) binds complement fragments C3b/C4b deposited on mycobacteria, mediating its entrance in macrophages. We investigated CR1 polymorphisms, gene e...

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Detalles Bibliográficos
Autores principales:	Kretzschmar, Gabriela Canalli, Oliveira, Luana Caroline, Nisihara, Renato Mitsunori, Velavan, Thirumalaisamy P., Stinghen, Sérvio Túlio, Stahlke, Ewalda R. S., Petzl-Erler, Maria Luiza, de Messias-Reason, Iara José T., Boldt, Angelica Beate Winter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103516/ https://www.ncbi.nlm.nih.gov/pubmed/30092084 http://dx.doi.org/10.1371/journal.pntd.0006705

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