Injection of an SV40 transcriptional terminator causes embryonic lethality: a possible zebrafish model for screening nonhomologous end-joining inhibitors

INTRODUCTION: DNA repair by the nonhomologous end joining (NHEJ) pathway promotes tumor recurrence after chemotherapy and radiotherapy. Discovery of rapid and high-throughput techniques to screen for an effective NHEJ inhibitor drug is imperative for the suppression of NHEJ during tumor treatment. H...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Zhe, Chen, Shihao, Xue, Songlei, Li, Xinxiu, Hu, Jiang, Sun, Zhen, Cui, Hengmi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103608/
https://www.ncbi.nlm.nih.gov/pubmed/30154663
http://dx.doi.org/10.2147/OTT.S153576

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103608/
https://www.ncbi.nlm.nih.gov/pubmed/30154663
http://dx.doi.org/10.2147/OTT.S153576

Ejemplares similares