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Injection of an SV40 transcriptional terminator causes embryonic lethality: a possible zebrafish model for screening nonhomologous end-joining inhibitors
INTRODUCTION: DNA repair by the nonhomologous end joining (NHEJ) pathway promotes tumor recurrence after chemotherapy and radiotherapy. Discovery of rapid and high-throughput techniques to screen for an effective NHEJ inhibitor drug is imperative for the suppression of NHEJ during tumor treatment. H...
Autores principales: | Yang, Zhe, Chen, Shihao, Xue, Songlei, Li, Xinxiu, Hu, Jiang, Sun, Zhen, Cui, Hengmi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103608/ https://www.ncbi.nlm.nih.gov/pubmed/30154663 http://dx.doi.org/10.2147/OTT.S153576 |
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