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Multifocal motor neuropathy presenting as a post-infectious complication of dengue: a CASE report

BACKGROUND: Dengue infection is an endemic illness in the tropics and it is associated with a wide variety of post infectious complications. With the increasing prevalence of dengue infection in endemic regions, post-infectious neurological complications following dengue infection are now been repor...

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Autores principales: Higgoda, Rakitha, Perera, Dilshan, Thirumavalavan, Kanapathipillai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103970/
https://www.ncbi.nlm.nih.gov/pubmed/30134860
http://dx.doi.org/10.1186/s12879-018-3334-z
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author Higgoda, Rakitha
Perera, Dilshan
Thirumavalavan, Kanapathipillai
author_facet Higgoda, Rakitha
Perera, Dilshan
Thirumavalavan, Kanapathipillai
author_sort Higgoda, Rakitha
collection PubMed
description BACKGROUND: Dengue infection is an endemic illness in the tropics and it is associated with a wide variety of post infectious complications. With the increasing prevalence of dengue infection in endemic regions, post-infectious neurological complications following dengue infection are now been reported more frequently. We report a patient who developed multifocal motor neuropathy (MMN) with conduction blocks following dengue infection during the immediate post-infectious period. MMN is a rare neurological disorder with an autoimmune etiology and to best of our knowledge this is the first reported case of MMN occurring following dengue infection as a post dengue neurological complication. CASE PRESENTATION: A 20 year old Sri Lankan male who was treated for serologically confirmed dengue infection presented to us with 1 month history of bilateral hand weakness which has started 5 days after the dengue infection (5 days after the discharge). On examination he had asymmetrical motor weakness of the hands and to a lesser degree in feet. There was no sensory impairment. Nerve conduction studies confirmed MMN with conduction blocks. He was started on intravenous immunoglobulin therapy for which he showed a good response. CONCLUSION: The authors report the first case of MMN complicating dengue fever in a previously healthy male from Sri Lanka. Thus it should be borne in mind that although rare, MMN can occur as a post-infectious complication of dengue fever.
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spelling pubmed-61039702018-08-30 Multifocal motor neuropathy presenting as a post-infectious complication of dengue: a CASE report Higgoda, Rakitha Perera, Dilshan Thirumavalavan, Kanapathipillai BMC Infect Dis Case Report BACKGROUND: Dengue infection is an endemic illness in the tropics and it is associated with a wide variety of post infectious complications. With the increasing prevalence of dengue infection in endemic regions, post-infectious neurological complications following dengue infection are now been reported more frequently. We report a patient who developed multifocal motor neuropathy (MMN) with conduction blocks following dengue infection during the immediate post-infectious period. MMN is a rare neurological disorder with an autoimmune etiology and to best of our knowledge this is the first reported case of MMN occurring following dengue infection as a post dengue neurological complication. CASE PRESENTATION: A 20 year old Sri Lankan male who was treated for serologically confirmed dengue infection presented to us with 1 month history of bilateral hand weakness which has started 5 days after the dengue infection (5 days after the discharge). On examination he had asymmetrical motor weakness of the hands and to a lesser degree in feet. There was no sensory impairment. Nerve conduction studies confirmed MMN with conduction blocks. He was started on intravenous immunoglobulin therapy for which he showed a good response. CONCLUSION: The authors report the first case of MMN complicating dengue fever in a previously healthy male from Sri Lanka. Thus it should be borne in mind that although rare, MMN can occur as a post-infectious complication of dengue fever. BioMed Central 2018-08-22 /pmc/articles/PMC6103970/ /pubmed/30134860 http://dx.doi.org/10.1186/s12879-018-3334-z Text en © The Author(s). 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Case Report
Higgoda, Rakitha
Perera, Dilshan
Thirumavalavan, Kanapathipillai
Multifocal motor neuropathy presenting as a post-infectious complication of dengue: a CASE report
title Multifocal motor neuropathy presenting as a post-infectious complication of dengue: a CASE report
title_full Multifocal motor neuropathy presenting as a post-infectious complication of dengue: a CASE report
title_fullStr Multifocal motor neuropathy presenting as a post-infectious complication of dengue: a CASE report
title_full_unstemmed Multifocal motor neuropathy presenting as a post-infectious complication of dengue: a CASE report
title_short Multifocal motor neuropathy presenting as a post-infectious complication of dengue: a CASE report
title_sort multifocal motor neuropathy presenting as a post-infectious complication of dengue: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103970/
https://www.ncbi.nlm.nih.gov/pubmed/30134860
http://dx.doi.org/10.1186/s12879-018-3334-z
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