Hit hard and early: analysing the effects of high-dose methylprednisolone on nailfold capillary changes and biomarkers in very early systemic sclerosis: study protocol for a 12-week randomised controlled trial

BACKGROUND: Mounting evidence indicates that inflammatory mechanisms drive systemic sclerosis (SSc) vasculopathy and fibrosis, especially early in the disease. Therefore, patients with very early SSc could benefit from early treatments targeting inflammation. Glucocorticoids are among the most poten...

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Detalles Bibliográficos
Autores principales: van den Hombergh, Wieneke M. T., Kersten, Brigit E., Knaapen-Hans, Hanneke K. A., Thurlings, Rogier M., van der Kraan, Peter M., van den Hoogen, Frank H. J., Fransen, Jaap, Vonk, Madelon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Study Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104002/
https://www.ncbi.nlm.nih.gov/pubmed/30134971
http://dx.doi.org/10.1186/s13063-018-2798-x

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