Lgl1 controls NG2 endocytic pathway to regulate oligodendrocyte differentiation and asymmetric cell division and gliomagenesis

Oligodendrocyte progenitor cells (OPC) undergo asymmetric cell division (ACD) to generate one OPC and one differentiating oligodendrocyte (OL) progeny. Loss of pro-mitotic proteoglycan and OPC marker NG2 in the OL progeny is the earliest immunophenotypic change of unknown mechanism that indicates di...

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Detalles Bibliográficos
Autores principales: Daynac, Mathieu, Chouchane, Malek, Collins, Hannah Y., Murphy, Nicole E., Andor, Noemi, Niu, Jianqin, Fancy, Stephen P. J., Stallcup, William B., Petritsch, Claudia K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104045/
https://www.ncbi.nlm.nih.gov/pubmed/30131568
http://dx.doi.org/10.1038/s41467-018-05099-3

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