Altered dopamine release and monoamine transporters in Vps35 p.D620N knock-in mice

Vacuolar protein sorting 35 (VPS35) is a core component of the retromer trimer required for endosomal membrane-associated protein trafficking. The discovery of a missense mutation, Vps35 p.D620N implicates retromer dysfunction in the pathogenesis of Parkinson’s disease (PD). We have characterized a...

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Detalles Bibliográficos
Autores principales: Cataldi, Stefano, Follett, Jordan, Fox, Jesse D., Tatarnikov, Igor, Kadgien, Chelsie, Gustavsson, Emil K., Khinda, Jaskaran, Milnerwood, Austen J., Farrer, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104078/
https://www.ncbi.nlm.nih.gov/pubmed/30155515
http://dx.doi.org/10.1038/s41531-018-0063-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104078/
https://www.ncbi.nlm.nih.gov/pubmed/30155515
http://dx.doi.org/10.1038/s41531-018-0063-3

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