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Altered dopamine release and monoamine transporters in Vps35 p.D620N knock-in mice
Vacuolar protein sorting 35 (VPS35) is a core component of the retromer trimer required for endosomal membrane-associated protein trafficking. The discovery of a missense mutation, Vps35 p.D620N implicates retromer dysfunction in the pathogenesis of Parkinson’s disease (PD). We have characterized a...
Autores principales: | Cataldi, Stefano, Follett, Jordan, Fox, Jesse D., Tatarnikov, Igor, Kadgien, Chelsie, Gustavsson, Emil K., Khinda, Jaskaran, Milnerwood, Austen J., Farrer, Matthew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104078/ https://www.ncbi.nlm.nih.gov/pubmed/30155515 http://dx.doi.org/10.1038/s41531-018-0063-3 |
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