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Recent advances in screening of enzymes inhibitors based on capillary electrophoresis
Capillary electrophoresis with many advantages plays an important role in pharmaceutical analysis and drug screening. This review gives an overview on the recent advances in the developments and applications of capillary electrophoresis in the field of enzyme inhibitor screening. The period covers 2...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Xi'an Jiaotong University
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104152/ https://www.ncbi.nlm.nih.gov/pubmed/30140486 http://dx.doi.org/10.1016/j.jpha.2018.05.002 |
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author | Cheng, Mengxia Chen, Zilin |
author_facet | Cheng, Mengxia Chen, Zilin |
author_sort | Cheng, Mengxia |
collection | PubMed |
description | Capillary electrophoresis with many advantages plays an important role in pharmaceutical analysis and drug screening. This review gives an overview on the recent advances in the developments and applications of capillary electrophoresis in the field of enzyme inhibitor screening. The period covers 2013 to 2017. Both the pre-capillary enzyme assays and in-capillary enzyme assays which include electrophoretically mediated microanalysis (EMMA) and immobilized enzyme microreactor (IMER) are summarized in this article. |
format | Online Article Text |
id | pubmed-6104152 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Xi'an Jiaotong University |
record_format | MEDLINE/PubMed |
spelling | pubmed-61041522018-08-23 Recent advances in screening of enzymes inhibitors based on capillary electrophoresis Cheng, Mengxia Chen, Zilin J Pharm Anal Review Paper Capillary electrophoresis with many advantages plays an important role in pharmaceutical analysis and drug screening. This review gives an overview on the recent advances in the developments and applications of capillary electrophoresis in the field of enzyme inhibitor screening. The period covers 2013 to 2017. Both the pre-capillary enzyme assays and in-capillary enzyme assays which include electrophoretically mediated microanalysis (EMMA) and immobilized enzyme microreactor (IMER) are summarized in this article. Xi'an Jiaotong University 2018-08 2018-05-11 /pmc/articles/PMC6104152/ /pubmed/30140486 http://dx.doi.org/10.1016/j.jpha.2018.05.002 Text en © 2018 Xi'an Jiaotong University. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Paper Cheng, Mengxia Chen, Zilin Recent advances in screening of enzymes inhibitors based on capillary electrophoresis |
title | Recent advances in screening of enzymes inhibitors based on capillary electrophoresis |
title_full | Recent advances in screening of enzymes inhibitors based on capillary electrophoresis |
title_fullStr | Recent advances in screening of enzymes inhibitors based on capillary electrophoresis |
title_full_unstemmed | Recent advances in screening of enzymes inhibitors based on capillary electrophoresis |
title_short | Recent advances in screening of enzymes inhibitors based on capillary electrophoresis |
title_sort | recent advances in screening of enzymes inhibitors based on capillary electrophoresis |
topic | Review Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104152/ https://www.ncbi.nlm.nih.gov/pubmed/30140486 http://dx.doi.org/10.1016/j.jpha.2018.05.002 |
work_keys_str_mv | AT chengmengxia recentadvancesinscreeningofenzymesinhibitorsbasedoncapillaryelectrophoresis AT chenzilin recentadvancesinscreeningofenzymesinhibitorsbasedoncapillaryelectrophoresis |