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WWOX Phosphorylation, Signaling, and Role in Neurodegeneration

Homozygous null mutation of tumor suppressor WWOX/Wwox gene leads to severe neural diseases, metabolic disorders and early death in the newborns of humans, mice and rats. WWOX is frequently downregulated in the hippocampi of patients with Alzheimer’s disease (AD). In vitro analysis revealed that kno...

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Detalles Bibliográficos
Autores principales:	Liu, Chan-Chuan, Ho, Pei-Chuan, Lee, I.-Ting, Chen, Yu-An, Chu, Chun-Hsien, Teng, Chih-Chuan, Wu, Sheng-Nan, Sze, Chun-I., Chiang, Ming-Fu, Chang, Nan-Shan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104168/ https://www.ncbi.nlm.nih.gov/pubmed/30158849 http://dx.doi.org/10.3389/fnins.2018.00563

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