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Generation of transgenic mouse line with prostate-specific expression of codon-improved Cre recombinase
BACKGROUND: Genetically engineered mouse models are useful tools to decipher molecular mechanisms of diseases. As for prostates, a rat probasin promoter has been widely used to drive prostate-specific gene expression. To optimize its codon usage to that of mammals, we used codon-improved Cre recombi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Asian Pacific Prostate Society
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104291/ https://www.ncbi.nlm.nih.gov/pubmed/30140659 http://dx.doi.org/10.1016/j.prnil.2018.04.003 |