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Metformin added to bosentan therapy in patients with pulmonary arterial hypertension associated with congenital heart defects: a pilot study

Pulmonary arterial hypertension (PAH) is a common complication of a congenital heart defect (CHD). Recent studies suggest metformin may be a potential drug to improve cardiac function in PAH. A pilot study was conducted to investigate the efficacy of short-term treatment with a combination regimen c...

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Detalles Bibliográficos
Autores principales: Liao, Shutan, Li, Dongsheng, Hui, Zheng, McLachlan, Craig S., Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104295/
https://www.ncbi.nlm.nih.gov/pubmed/30151369
http://dx.doi.org/10.1183/23120541.00060-2018