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Roles of Microglial and Monocyte Chemokines and Their Receptors in Regulating Alzheimer's Disease-Associated Amyloid-β and Tau Pathologies

Chemokines and their receptors have been shown to affect amyloid-β (Aβ) and tau pathologies in mouse models of Alzheimer's disease (AD) by regulating microglia and monocyte-associated neuroinflammation, microglial movement and monocyte recruitment into the brain. These cells in turn can promote...

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Detalles Bibliográficos
Autores principales: Guedes, Joana R., Lao, Taotao, Cardoso, Ana L., El Khoury, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104478/
https://www.ncbi.nlm.nih.gov/pubmed/30158892
http://dx.doi.org/10.3389/fneur.2018.00549

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