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Antibiotic misuse among university students in developed and less developed regions of China: a cross-sectional survey

Background: Antimicrobial resistance (AMR) is a great threat to public health. The primary cause of AMR is human antibiotic misuse. Little is known about regional differences of antibiotic misuse behaviours in China. Objectives: To explore the antibiotic misuse behaviours among university students i...

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Autores principales: Peng, Dandan, Wang, Xiaomin, Xu, Yannan, Sun, Chenhui, Zhou, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104601/
https://www.ncbi.nlm.nih.gov/pubmed/30132407
http://dx.doi.org/10.1080/16549716.2018.1496973
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author Peng, Dandan
Wang, Xiaomin
Xu, Yannan
Sun, Chenhui
Zhou, Xudong
author_facet Peng, Dandan
Wang, Xiaomin
Xu, Yannan
Sun, Chenhui
Zhou, Xudong
author_sort Peng, Dandan
collection PubMed
description Background: Antimicrobial resistance (AMR) is a great threat to public health. The primary cause of AMR is human antibiotic misuse. Little is known about regional differences of antibiotic misuse behaviours in China. Objectives: To explore the antibiotic misuse behaviours among university students in western and eastern China and find out the regional differences. Methods: Participants were recruited from universities in less developed Guizhou Province and developed Zhejiang Province using a cluster random sampling method. A self-administered questionnaire was designed to collect data, and the χ(2) test and logistic regression were adopted to assess the associations between region and antibiotic misuse behaviours. Results: A total of 2073 university students from Guizhou and 1922 from Zhejiang completed questionnaires. Students in Guizhou had lower household income, parents’ education, and urban residence proportion than those in Zhejiang. Compared with those in Zhejiang, students in Guizhou had higher antibiotic use prescribed by doctors (79.8% vs 56.2%) and self-medication with antibiotics (33.0% vs 16.1%). Students in Guizhou were more likely to buy over-the-counter antibiotics without prescriptions (73.9% vs 63.4%), ask for antibiotics from doctors (21.4% vs 15.6%), and use antibiotics prophylactically (29.9% vs 15.7%). Adjusted models showed that the less developed region was significantly associated with higher antibiotic misuse behaviours. Conclusions: Misuse of antibiotics by well-educated young adults was very high in two regions but most serious in the less developed one. Campaigns are urgently needed to promote appropriate antibiotic use especially in less developed regions.
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spelling pubmed-61046012018-08-27 Antibiotic misuse among university students in developed and less developed regions of China: a cross-sectional survey Peng, Dandan Wang, Xiaomin Xu, Yannan Sun, Chenhui Zhou, Xudong Glob Health Action Original Article Background: Antimicrobial resistance (AMR) is a great threat to public health. The primary cause of AMR is human antibiotic misuse. Little is known about regional differences of antibiotic misuse behaviours in China. Objectives: To explore the antibiotic misuse behaviours among university students in western and eastern China and find out the regional differences. Methods: Participants were recruited from universities in less developed Guizhou Province and developed Zhejiang Province using a cluster random sampling method. A self-administered questionnaire was designed to collect data, and the χ(2) test and logistic regression were adopted to assess the associations between region and antibiotic misuse behaviours. Results: A total of 2073 university students from Guizhou and 1922 from Zhejiang completed questionnaires. Students in Guizhou had lower household income, parents’ education, and urban residence proportion than those in Zhejiang. Compared with those in Zhejiang, students in Guizhou had higher antibiotic use prescribed by doctors (79.8% vs 56.2%) and self-medication with antibiotics (33.0% vs 16.1%). Students in Guizhou were more likely to buy over-the-counter antibiotics without prescriptions (73.9% vs 63.4%), ask for antibiotics from doctors (21.4% vs 15.6%), and use antibiotics prophylactically (29.9% vs 15.7%). Adjusted models showed that the less developed region was significantly associated with higher antibiotic misuse behaviours. Conclusions: Misuse of antibiotics by well-educated young adults was very high in two regions but most serious in the less developed one. Campaigns are urgently needed to promote appropriate antibiotic use especially in less developed regions. Taylor & Francis 2018-08-22 /pmc/articles/PMC6104601/ /pubmed/30132407 http://dx.doi.org/10.1080/16549716.2018.1496973 Text en © 2018 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Peng, Dandan
Wang, Xiaomin
Xu, Yannan
Sun, Chenhui
Zhou, Xudong
Antibiotic misuse among university students in developed and less developed regions of China: a cross-sectional survey
title Antibiotic misuse among university students in developed and less developed regions of China: a cross-sectional survey
title_full Antibiotic misuse among university students in developed and less developed regions of China: a cross-sectional survey
title_fullStr Antibiotic misuse among university students in developed and less developed regions of China: a cross-sectional survey
title_full_unstemmed Antibiotic misuse among university students in developed and less developed regions of China: a cross-sectional survey
title_short Antibiotic misuse among university students in developed and less developed regions of China: a cross-sectional survey
title_sort antibiotic misuse among university students in developed and less developed regions of china: a cross-sectional survey
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104601/
https://www.ncbi.nlm.nih.gov/pubmed/30132407
http://dx.doi.org/10.1080/16549716.2018.1496973
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