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Canine rhinitis caused by an uncommonly-diagnosed fungus, Scedosporium apiospermum

A Golden Retriever cross was presented with a four week history of violent sneezing and licking at the nasal planum. Nasal mycosis was diagnosed and Aspergillus sp. presumed the causative agent, until culture, PCR and DNA sequencing showed that Scedosporium apiospermum, an uncommonly diagnosed, yet...

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Detalles Bibliográficos
Autores principales: Smith, Christopher G., Woolford, Lucy, Talbot, Jessica J., Lee, Ken C., Crocker, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104628/
https://www.ncbi.nlm.nih.gov/pubmed/30140605
http://dx.doi.org/10.1016/j.mmcr.2018.08.004
Descripción
Sumario:A Golden Retriever cross was presented with a four week history of violent sneezing and licking at the nasal planum. Nasal mycosis was diagnosed and Aspergillus sp. presumed the causative agent, until culture, PCR and DNA sequencing showed that Scedosporium apiospermum, an uncommonly diagnosed, yet emerging, fungal pathogen, was the agent responsible. Debridement of the fungal plaques and systemic itraconazole therapy resulted in complete resolution of clinical disease. We discuss the current literature on S. apiospermum, review its clinical significance and question the validity of its ‘complex’ taxonomy.