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Candida auris, what do paediatricians need to know?

The newly recognised and emerging fungal species, Candida auris, has caused worldwide invasive infections and has been implicated in difficult to control hospital outbreaks. Challenges are encountered in the correct identification of this fungus as commonly used phenotypic and biochemical methods fa...

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Detalles Bibliográficos
Autor principal: Warris, Adilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104675/
https://www.ncbi.nlm.nih.gov/pubmed/29545411
http://dx.doi.org/10.1136/archdischild-2017-313960
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author Warris, Adilia
author_facet Warris, Adilia
author_sort Warris, Adilia
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description The newly recognised and emerging fungal species, Candida auris, has caused worldwide invasive infections and has been implicated in difficult to control hospital outbreaks. Challenges are encountered in the correct identification of this fungus as commonly used phenotypic and biochemical methods fail to differentiate C. auris from other Candida species. Its resistance profile, over 90% of isolates are fluconazole resistant and 35% are resistant to amphotericin, confronts clinicians with the restricted arsenal of antifungals and concerns about optimal treatment. The very first C. auris isolate was recovered from a paediatric patient in retrospect. Although infections with the more antifungal-resistant Candida species are less frequently observed in paediatric patients, this seems to be different for C. auris infections.
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spelling pubmed-61046752018-08-24 Candida auris, what do paediatricians need to know? Warris, Adilia Arch Dis Child Review The newly recognised and emerging fungal species, Candida auris, has caused worldwide invasive infections and has been implicated in difficult to control hospital outbreaks. Challenges are encountered in the correct identification of this fungus as commonly used phenotypic and biochemical methods fail to differentiate C. auris from other Candida species. Its resistance profile, over 90% of isolates are fluconazole resistant and 35% are resistant to amphotericin, confronts clinicians with the restricted arsenal of antifungals and concerns about optimal treatment. The very first C. auris isolate was recovered from a paediatric patient in retrospect. Although infections with the more antifungal-resistant Candida species are less frequently observed in paediatric patients, this seems to be different for C. auris infections. BMJ Publishing Group 2018-09 2018-03-15 /pmc/articles/PMC6104675/ /pubmed/29545411 http://dx.doi.org/10.1136/archdischild-2017-313960 Text en © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted. This is an open access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: http://creativecommons.org/licenses/by/4.0/
spellingShingle Review
Warris, Adilia
Candida auris, what do paediatricians need to know?
title Candida auris, what do paediatricians need to know?
title_full Candida auris, what do paediatricians need to know?
title_fullStr Candida auris, what do paediatricians need to know?
title_full_unstemmed Candida auris, what do paediatricians need to know?
title_short Candida auris, what do paediatricians need to know?
title_sort candida auris, what do paediatricians need to know?
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104675/
https://www.ncbi.nlm.nih.gov/pubmed/29545411
http://dx.doi.org/10.1136/archdischild-2017-313960
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