Cargando…

Sudden Sensorineural Hearing Loss in Children: A Report of 75 Cases

OBJECTIVE: To investigate the characteristics, treatment, and prognostic factors of sudden sensorineural hearing loss (SSNHL) in children. METHODS: Seventy-five cases (78 ears) of SSNHL in children from February 2011 to June 2016 were retrospectively analyzed. We scrutinized the clinical manifestati...

Descripción completa

Detalles Bibliográficos
Autores principales: Qian, Yi, Zhong, Shixun, Hu, Guohua, Kang, Houyong, Wang, Ling, Lei, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104722/
https://www.ncbi.nlm.nih.gov/pubmed/30063499
http://dx.doi.org/10.1097/MAO.0000000000001891
_version_ 1783349540625055744
author Qian, Yi
Zhong, Shixun
Hu, Guohua
Kang, Houyong
Wang, Ling
Lei, Yan
author_facet Qian, Yi
Zhong, Shixun
Hu, Guohua
Kang, Houyong
Wang, Ling
Lei, Yan
author_sort Qian, Yi
collection PubMed
description OBJECTIVE: To investigate the characteristics, treatment, and prognostic factors of sudden sensorineural hearing loss (SSNHL) in children. METHODS: Seventy-five cases (78 ears) of SSNHL in children from February 2011 to June 2016 were retrospectively analyzed. We scrutinized the clinical manifestations, audiological assessments, and serologic examinations of these pediatric cases by univariate and multivariate logistic analysis methods. The patients were divided into four groups according to their audiometric curve type: ascending, descending, flat, and profound. RESULTS: Of the 75 patients (78 ears), 25 patients were in the ascending group (32.00%), 9 patients were in the descending group (12.00%), 17 patients were in the flat group (22.67%), and 24 patients were in the profound group (32.32%). The overall recovery rates (complete + partial + slight) of the different groups were as follows: ascending group, 96.00%; flat group, 76.47%; profound group, 50.00%; and descending group, 44.44%. The overall recovery rate of all patients was 70.67%. The multivariate logistic analysis showed that the type of audiometric curve and the interval from onset to intervention were two independent risk factors that correlated with the prognosis of SSNHL in children. Some children had positive cytomegaoviyns, rubella virus, and herpes simplex virus immunoglobulin G antibodies. Twenty-one children were treated with additional intratympanic methylprednisolone as salvage therapy and 13 of these children showed improved (complete + partial + slight) recoveries. Three children had postauricular compound betamethasone injections, but none of them showed improvement. One of three children recovered slightly after treatment with intratympanic methylprednisolone combined with postauricular betamethasone injection. CONCLUSIONS: The prognosis of SSNHL in children is closely related to the type of audiometric curve and the onset of treatment. Intratympanic methylprednisolone and compound betamethasone injected postauricularly could be effective for SSNHL in children.
format Online
Article
Text
id pubmed-6104722
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Lippincott Williams & Wilkins
record_format MEDLINE/PubMed
spelling pubmed-61047222018-09-07 Sudden Sensorineural Hearing Loss in Children: A Report of 75 Cases Qian, Yi Zhong, Shixun Hu, Guohua Kang, Houyong Wang, Ling Lei, Yan Otol Neurotol Pediatric Otology OBJECTIVE: To investigate the characteristics, treatment, and prognostic factors of sudden sensorineural hearing loss (SSNHL) in children. METHODS: Seventy-five cases (78 ears) of SSNHL in children from February 2011 to June 2016 were retrospectively analyzed. We scrutinized the clinical manifestations, audiological assessments, and serologic examinations of these pediatric cases by univariate and multivariate logistic analysis methods. The patients were divided into four groups according to their audiometric curve type: ascending, descending, flat, and profound. RESULTS: Of the 75 patients (78 ears), 25 patients were in the ascending group (32.00%), 9 patients were in the descending group (12.00%), 17 patients were in the flat group (22.67%), and 24 patients were in the profound group (32.32%). The overall recovery rates (complete + partial + slight) of the different groups were as follows: ascending group, 96.00%; flat group, 76.47%; profound group, 50.00%; and descending group, 44.44%. The overall recovery rate of all patients was 70.67%. The multivariate logistic analysis showed that the type of audiometric curve and the interval from onset to intervention were two independent risk factors that correlated with the prognosis of SSNHL in children. Some children had positive cytomegaoviyns, rubella virus, and herpes simplex virus immunoglobulin G antibodies. Twenty-one children were treated with additional intratympanic methylprednisolone as salvage therapy and 13 of these children showed improved (complete + partial + slight) recoveries. Three children had postauricular compound betamethasone injections, but none of them showed improvement. One of three children recovered slightly after treatment with intratympanic methylprednisolone combined with postauricular betamethasone injection. CONCLUSIONS: The prognosis of SSNHL in children is closely related to the type of audiometric curve and the onset of treatment. Intratympanic methylprednisolone and compound betamethasone injected postauricularly could be effective for SSNHL in children. Lippincott Williams & Wilkins 2018-09 2018-08-15 /pmc/articles/PMC6104722/ /pubmed/30063499 http://dx.doi.org/10.1097/MAO.0000000000001891 Text en Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of Otology & Neurotology, Inc. http://creativecommons.org/licenses/by-nc-nd/4.0 This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0
spellingShingle Pediatric Otology
Qian, Yi
Zhong, Shixun
Hu, Guohua
Kang, Houyong
Wang, Ling
Lei, Yan
Sudden Sensorineural Hearing Loss in Children: A Report of 75 Cases
title Sudden Sensorineural Hearing Loss in Children: A Report of 75 Cases
title_full Sudden Sensorineural Hearing Loss in Children: A Report of 75 Cases
title_fullStr Sudden Sensorineural Hearing Loss in Children: A Report of 75 Cases
title_full_unstemmed Sudden Sensorineural Hearing Loss in Children: A Report of 75 Cases
title_short Sudden Sensorineural Hearing Loss in Children: A Report of 75 Cases
title_sort sudden sensorineural hearing loss in children: a report of 75 cases
topic Pediatric Otology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104722/
https://www.ncbi.nlm.nih.gov/pubmed/30063499
http://dx.doi.org/10.1097/MAO.0000000000001891
work_keys_str_mv AT qianyi suddensensorineuralhearinglossinchildrenareportof75cases
AT zhongshixun suddensensorineuralhearinglossinchildrenareportof75cases
AT huguohua suddensensorineuralhearinglossinchildrenareportof75cases
AT kanghouyong suddensensorineuralhearinglossinchildrenareportof75cases
AT wangling suddensensorineuralhearinglossinchildrenareportof75cases
AT leiyan suddensensorineuralhearinglossinchildrenareportof75cases