Cargando…

Substantial Heterogeneity in Progress Toward Reaching the 90-90-90 HIV Target in the WHO European Region

BACKGROUND: Achieving the UNAIDS 90-90-90 target by 2020 is expected to end the HIV epidemic by 2030. We report on progress in the WHO European Region in meeting this target. METHODS: The European Centre for Disease Prevention and Control (ECDC) sent questionnaires to 55 countries in 2016. We report...

Descripción completa

Detalles Bibliográficos
Autores principales: Porter, Kholoud, Gourlay, Annabelle, Attawell, Kathy, Hales, David, Supervie, Virginie, Touloumi, Giota, Rosinska, Magda, Vourli, Georgia, van Sighem, Ard, Pharris, Anastasia, Noori, Teymur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: JAIDS Journal of Acquired Immune Deficiency Syndromes 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104723/
https://www.ncbi.nlm.nih.gov/pubmed/29847474
http://dx.doi.org/10.1097/QAI.0000000000001761
_version_ 1783349540862033920
author Porter, Kholoud
Gourlay, Annabelle
Attawell, Kathy
Hales, David
Supervie, Virginie
Touloumi, Giota
Rosinska, Magda
Vourli, Georgia
van Sighem, Ard
Pharris, Anastasia
Noori, Teymur
author_facet Porter, Kholoud
Gourlay, Annabelle
Attawell, Kathy
Hales, David
Supervie, Virginie
Touloumi, Giota
Rosinska, Magda
Vourli, Georgia
van Sighem, Ard
Pharris, Anastasia
Noori, Teymur
author_sort Porter, Kholoud
collection PubMed
description BACKGROUND: Achieving the UNAIDS 90-90-90 target by 2020 is expected to end the HIV epidemic by 2030. We report on progress in the WHO European Region in meeting this target. METHODS: The European Centre for Disease Prevention and Control (ECDC) sent questionnaires to 55 countries in 2016. We report estimates for 4 stages of the continuum of HIV care (living with HIV, diagnosed, treated, and virally suppressed), corresponding to the Joint United Nations Programme on HIV and AIDS (UNAIDS) target and explore differences by subregion and challenges with reporting data. FINDINGS: Forty-four countries provided data for ≥1 stage, and 29 for all 4 stages. Estimated HIV prevalence was 0.19% (range 0.02%–0.84%, n = 37 countries providing stage 1 data). The proportion diagnosed of people living with HIV ranged from 38% to 98% (n = 37 reporting number of people living with HIV and diagnosed). The proportion on ART of those diagnosed ranged from 27% to 96% (n = 40 reporting numbers diagnosed and treated), and viral suppression rates ranged from 32% to 97% (n = 31 providing numbers treated and virally suppressed). The overall continuum of care estimate for 29 countries with complete data was 81-84-88, which differed by subregion: 84-88-90, 84-69-62, and 57-45-57 for the western, central, and eastern subregions, respectively. Challenges in reporting data included absence of a single data source for all stages, shortage of expertise, and lack of financial and human resources. CONCLUSIONS: There is an urgent need to strengthen HIV testing programs throughout Europe, particularly in the eastern subregion, and to remove constraints hampering access to testing and care. Recent changes to treatment guidelines should help reduce the numbers diagnosed not treated.
format Online
Article
Text
id pubmed-6104723
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher JAIDS Journal of Acquired Immune Deficiency Syndromes
record_format MEDLINE/PubMed
spelling pubmed-61047232018-09-07 Substantial Heterogeneity in Progress Toward Reaching the 90-90-90 HIV Target in the WHO European Region Porter, Kholoud Gourlay, Annabelle Attawell, Kathy Hales, David Supervie, Virginie Touloumi, Giota Rosinska, Magda Vourli, Georgia van Sighem, Ard Pharris, Anastasia Noori, Teymur J Acquir Immune Defic Syndr Epidemiology BACKGROUND: Achieving the UNAIDS 90-90-90 target by 2020 is expected to end the HIV epidemic by 2030. We report on progress in the WHO European Region in meeting this target. METHODS: The European Centre for Disease Prevention and Control (ECDC) sent questionnaires to 55 countries in 2016. We report estimates for 4 stages of the continuum of HIV care (living with HIV, diagnosed, treated, and virally suppressed), corresponding to the Joint United Nations Programme on HIV and AIDS (UNAIDS) target and explore differences by subregion and challenges with reporting data. FINDINGS: Forty-four countries provided data for ≥1 stage, and 29 for all 4 stages. Estimated HIV prevalence was 0.19% (range 0.02%–0.84%, n = 37 countries providing stage 1 data). The proportion diagnosed of people living with HIV ranged from 38% to 98% (n = 37 reporting number of people living with HIV and diagnosed). The proportion on ART of those diagnosed ranged from 27% to 96% (n = 40 reporting numbers diagnosed and treated), and viral suppression rates ranged from 32% to 97% (n = 31 providing numbers treated and virally suppressed). The overall continuum of care estimate for 29 countries with complete data was 81-84-88, which differed by subregion: 84-88-90, 84-69-62, and 57-45-57 for the western, central, and eastern subregions, respectively. Challenges in reporting data included absence of a single data source for all stages, shortage of expertise, and lack of financial and human resources. CONCLUSIONS: There is an urgent need to strengthen HIV testing programs throughout Europe, particularly in the eastern subregion, and to remove constraints hampering access to testing and care. Recent changes to treatment guidelines should help reduce the numbers diagnosed not treated. JAIDS Journal of Acquired Immune Deficiency Syndromes 2018-09-01 2018-08-14 /pmc/articles/PMC6104723/ /pubmed/29847474 http://dx.doi.org/10.1097/QAI.0000000000001761 Text en Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Epidemiology
Porter, Kholoud
Gourlay, Annabelle
Attawell, Kathy
Hales, David
Supervie, Virginie
Touloumi, Giota
Rosinska, Magda
Vourli, Georgia
van Sighem, Ard
Pharris, Anastasia
Noori, Teymur
Substantial Heterogeneity in Progress Toward Reaching the 90-90-90 HIV Target in the WHO European Region
title Substantial Heterogeneity in Progress Toward Reaching the 90-90-90 HIV Target in the WHO European Region
title_full Substantial Heterogeneity in Progress Toward Reaching the 90-90-90 HIV Target in the WHO European Region
title_fullStr Substantial Heterogeneity in Progress Toward Reaching the 90-90-90 HIV Target in the WHO European Region
title_full_unstemmed Substantial Heterogeneity in Progress Toward Reaching the 90-90-90 HIV Target in the WHO European Region
title_short Substantial Heterogeneity in Progress Toward Reaching the 90-90-90 HIV Target in the WHO European Region
title_sort substantial heterogeneity in progress toward reaching the 90-90-90 hiv target in the who european region
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104723/
https://www.ncbi.nlm.nih.gov/pubmed/29847474
http://dx.doi.org/10.1097/QAI.0000000000001761
work_keys_str_mv AT porterkholoud substantialheterogeneityinprogresstowardreachingthe909090hivtargetinthewhoeuropeanregion
AT gourlayannabelle substantialheterogeneityinprogresstowardreachingthe909090hivtargetinthewhoeuropeanregion
AT attawellkathy substantialheterogeneityinprogresstowardreachingthe909090hivtargetinthewhoeuropeanregion
AT halesdavid substantialheterogeneityinprogresstowardreachingthe909090hivtargetinthewhoeuropeanregion
AT supervievirginie substantialheterogeneityinprogresstowardreachingthe909090hivtargetinthewhoeuropeanregion
AT touloumigiota substantialheterogeneityinprogresstowardreachingthe909090hivtargetinthewhoeuropeanregion
AT rosinskamagda substantialheterogeneityinprogresstowardreachingthe909090hivtargetinthewhoeuropeanregion
AT vourligeorgia substantialheterogeneityinprogresstowardreachingthe909090hivtargetinthewhoeuropeanregion
AT vansighemard substantialheterogeneityinprogresstowardreachingthe909090hivtargetinthewhoeuropeanregion
AT pharrisanastasia substantialheterogeneityinprogresstowardreachingthe909090hivtargetinthewhoeuropeanregion
AT nooriteymur substantialheterogeneityinprogresstowardreachingthe909090hivtargetinthewhoeuropeanregion
AT substantialheterogeneityinprogresstowardreachingthe909090hivtargetinthewhoeuropeanregion