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Disruption of the Zdhhc9 intellectual disability gene leads to behavioural abnormalities in a mouse model

Protein S-acylation is a widespread post-translational modification that regulates the trafficking and function of a diverse array of proteins. This modification is catalysed by a family of twenty-three zDHHC enzymes that exhibit both specific and overlapping substrate interactions. Mutations in the...

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Detalles Bibliográficos
Autores principales: Kouskou, Marianna, Thomson, David M., Brett, Ros R., Wheeler, Lee, Tate, Rothwelle J., Pratt, Judith A., Chamberlain, Luke H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104741/
https://www.ncbi.nlm.nih.gov/pubmed/29944857
http://dx.doi.org/10.1016/j.expneurol.2018.06.014