PD-1 Controls Follicular T Helper Cell Positioning and Function

Follicular T helper (Tfh) cells highly express the programmed cell death-1 (PD-1) molecule. Whereas inhibition of T cell receptor (TCR) signaling and CD28 co-stimulation is thought to be the primary mode of PD-1 functions, whether and how PD-1 regulates Tfh cell development and function is unclear....

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Detalles Bibliográficos
Autores principales: Shi, Jingwen, Hou, Shiyue, Fang, Qian, Liu, Xin, Liu, Xiaolong, Qi, Hai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104813/
https://www.ncbi.nlm.nih.gov/pubmed/30076099
http://dx.doi.org/10.1016/j.immuni.2018.06.012

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