Cargando…

Transcription factor ASCL2 is required for development of the glycogen trophoblast cell lineage

The basic helix-loop-helix (bHLH) transcription factor ASCL2 plays essential roles in diploid multipotent trophoblast progenitors, intestinal stem cells, follicular T-helper cells, as well as during epidermal development and myogenesis. During early development, Ascl2 expression is regulated by geno...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bogutz, Aaron B., Oh-McGinnis, Rosemary, Jacob, Karen J., Ho-Lau, Rita, Gu, Ting, Gertsenstein, Marina, Nagy, Andras, Lefebvre, Louis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105033/ https://www.ncbi.nlm.nih.gov/pubmed/30096149 http://dx.doi.org/10.1371/journal.pgen.1007587

Ejemplares similares

Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome
por: Oh-McGinnis, Rosemary, et al.
Publicado: (2010)

Maternal DNA Methylation Regulates Early Trophoblast Development
por: Branco, Miguel R., et al.
Publicado: (2016)

Evolution of imprinting via lineage-specific insertion of retroviral promoters
por: Bogutz, Aaron B., et al.
Publicado: (2019)

Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta
por: Tunster, S.J., et al.
Publicado: (2016)

The N terminus of Ascl1 underlies differing proneural activity of mouse and Xenopus Ascl1 proteins
por: Hardwick, Laura J.A., et al.
Publicado: (2018)

Valproic acid silencing of ascl1b/Ascl1 results in the failure of serotonergic differentiation in a zebrafish model of fetal valproate syndrome
por: Jacob, John, et al.
Publicado: (2014)

Microtubule assembly in meiotic extract requires glycogen
por: Groen, Aaron C., et al.
Publicado: (2011)

Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon
por: Wang, Bei, et al.
Publicado: (2009)

Ascl3 transcription factor marks a distinct progenitor lineage for non-neuronal support cells in the olfactory epithelium
por: Weng, Pei-Lun, et al.
Publicado: (2016)

ASCL1 activates neuronal stem cell-like lineage programming through remodeling of the chromatin landscape in prostate cancer
por: Nouruzi, Shaghayegh, et al.
Publicado: (2022)

Trophoblast lineage specification in the mammalian preimplantation embryo
por: Toyooka, Yayoi
Publicado: (2020)

Hyperactivated Wnt-β-catenin signaling in the absence of sFRP1 and sFRP5 disrupts trophoblast differentiation through repression of Ascl2
por: Bao, Haili, et al.
Publicado: (2020)

Tissue-specific alternative polyadenylation at the imprinted gene Mest regulates allelic usage at Copg2
por: MacIsaac, Julia L., et al.
Publicado: (2012)

Setdb1 is required for germline development and silencing of H3K9me3-marked endogenous retroviruses in primordial germ cells
por: Liu, Sheng, et al.
Publicado: (2014)

Bone Marrow Transplantation Results in Human Donor Blood Cells Acquiring and Displaying Mouse Recipient Class I MHC and CD45 Antigens on Their Surface
por: Yamanaka, Nobuko, et al.
Publicado: (2009)

Subcellular localisation modulates ubiquitylation and degradation of Ascl1
por: Gillotin, Sébastien, et al.
Publicado: (2018)

Injury-induced ASCL1 expression orchestrates a transitory cell state required for repair of the neonatal cerebellum
por: Bayin, N. Sumru, et al.
Publicado: (2021)

Identification of ASCL1 as a determinant for human iPSC-derived dopaminergic neurons
por: Earley, Aaron M., et al.
Publicado: (2021)

Advancing Digital Medicine with Wearables in the Wild
por: McGinnis, Ryan S., et al.
Publicado: (2022)

Retinoid Acid Specifies Neuronal Identity through Graded Expression of Ascl1
por: Jacob, John, et al.
Publicado: (2013)

Retinoid Acid Specifies Neuronal Identity through Graded Expression of Ascl1
por: Jacob, John, et al.
Publicado: (2013)

Polarity inversion reorganizes the stem cell compartment of the trophoblast lineage
por: Ozguldez, Hatice O., et al.
Publicado: (2023)

Efficient Generation of Germ Line Transmitting Chimeras from C57BL/6N ES Cells by Aggregation with Outbred Host Embryos
por: Gertsenstein, Marina, et al.
Publicado: (2010)

Transcriptional control of vertebrate neurogenesis by the proneural factor Ascl1
por: Vasconcelos, Francisca F., et al.
Publicado: (2014)

Oligodendrocyte development in the embryonic tuberal hypothalamus and the influence of Ascl1
por: Marsters, Candace M., et al.
Publicado: (2016)

The Potential of Targeting Brain Pathology with Ascl1/Mash1
por: Tang, Bor Luen
Publicado: (2017)

Glycogen synthase kinase 3 controls migration of the neural crest lineage in mouse and Xenopus
por: Gonzalez Malagon, Sandra G., et al.
Publicado: (2018)

CNS side effects of immune checkpoint inhibitors: preclinical models, genetics and multimodality therapy
por: McGinnis, Gwendolyn J, et al.
Publicado: (2017)

Generation of Induced Neuronal Cells by the Single Reprogramming Factor ASCL1
por: Chanda, Soham, et al.
Publicado: (2014)

Inhibition of Glioma Development by ASCL1-Mediated Direct Neuronal Reprogramming
por: Cheng, Xueyan, et al.
Publicado: (2019)

Epigenetic Editing of Ascl1 Gene in Neural Stem Cells by Optogenetics
por: Lo, Chiao-Ling, et al.
Publicado: (2017)

Introducing the Stem Cell ASCL2 Reporter STAR into Intestinal Organoids
por: Heinz, Maria C., et al.
Publicado: (2020)

Molecular Mechanisms Underlying Ascl1-Mediated Astrocyte-to-Neuron Conversion
por: Rao, Zhiping, et al.
Publicado: (2021)

A21 OVEREXPRESSION OF ASCL2 ALTERS DIFFERENTIATION IN ESOPHAGEAL ORGANOIDS
por: Hamilton, M, et al.
Publicado: (2022)

Function of Proneural Genes Ascl1 and Asense in Neurogenesis: How Similar Are They?
por: Soares, Diogo S., et al.
Publicado: (2022)

The proprotein convertase furin is required for trophoblast syncytialization
por: Zhou, Z, et al.
Publicado: (2013)

Identification of two distinct peptide-binding pockets in the SH3 domain of human mixed-lineage kinase 3
por: Kokoszka, Malgorzata E., et al.
Publicado: (2018)

Duox, Flotillin-2, and Src42A Are Required to Activate or Delimit the Spread of the Transcriptional Response to Epidermal Wounds in Drosophila
por: Juarez, Michelle T., et al.
Publicado: (2011)

Tubby is required for trafficking G protein-coupled receptors to neuronal cilia
por: Sun, Xun, et al.
Publicado: (2012)

Mercury and Autistic Gut Disease
por: McGinnis, WR
Publicado: (2001)

Cannot write session to /tmp/vufind_sessions/sess_sf911m4lghvvuvqtk9gvm8imdl