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Gestational Psittacosis Resulting in Neonatal Death Identified by Next-Generation RNA Sequencing of Postmortem, Formalin-Fixed Lung Tissue

Psittacosis is a rare zoonosis that can cause severe disease and adverse outcomes during pregnancy. We identified a previously elusive case of psittacosis causing premature delivery and infant death by next-generation RNA sequencing of postmortem tissues. Hypothesis-free pathogen detection in postmo...

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Detalles Bibliográficos
Autores principales: Paul, Litty, Comstock, Jessica, Edes, Kornelia, Schlaberg, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105100/
https://www.ncbi.nlm.nih.gov/pubmed/30151406
http://dx.doi.org/10.1093/ofid/ofy172
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author Paul, Litty
Comstock, Jessica
Edes, Kornelia
Schlaberg, Robert
author_facet Paul, Litty
Comstock, Jessica
Edes, Kornelia
Schlaberg, Robert
author_sort Paul, Litty
collection PubMed
description Psittacosis is a rare zoonosis that can cause severe disease and adverse outcomes during pregnancy. We identified a previously elusive case of psittacosis causing premature delivery and infant death by next-generation RNA sequencing of postmortem tissues. Hypothesis-free pathogen detection in postmortem specimens can increase the yield of epidemiologic and cause-of-death studies.
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spelling pubmed-61051002018-08-27 Gestational Psittacosis Resulting in Neonatal Death Identified by Next-Generation RNA Sequencing of Postmortem, Formalin-Fixed Lung Tissue Paul, Litty Comstock, Jessica Edes, Kornelia Schlaberg, Robert Open Forum Infect Dis Brief Report Psittacosis is a rare zoonosis that can cause severe disease and adverse outcomes during pregnancy. We identified a previously elusive case of psittacosis causing premature delivery and infant death by next-generation RNA sequencing of postmortem tissues. Hypothesis-free pathogen detection in postmortem specimens can increase the yield of epidemiologic and cause-of-death studies. Oxford University Press 2018-08-22 /pmc/articles/PMC6105100/ /pubmed/30151406 http://dx.doi.org/10.1093/ofid/ofy172 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Report
Paul, Litty
Comstock, Jessica
Edes, Kornelia
Schlaberg, Robert
Gestational Psittacosis Resulting in Neonatal Death Identified by Next-Generation RNA Sequencing of Postmortem, Formalin-Fixed Lung Tissue
title Gestational Psittacosis Resulting in Neonatal Death Identified by Next-Generation RNA Sequencing of Postmortem, Formalin-Fixed Lung Tissue
title_full Gestational Psittacosis Resulting in Neonatal Death Identified by Next-Generation RNA Sequencing of Postmortem, Formalin-Fixed Lung Tissue
title_fullStr Gestational Psittacosis Resulting in Neonatal Death Identified by Next-Generation RNA Sequencing of Postmortem, Formalin-Fixed Lung Tissue
title_full_unstemmed Gestational Psittacosis Resulting in Neonatal Death Identified by Next-Generation RNA Sequencing of Postmortem, Formalin-Fixed Lung Tissue
title_short Gestational Psittacosis Resulting in Neonatal Death Identified by Next-Generation RNA Sequencing of Postmortem, Formalin-Fixed Lung Tissue
title_sort gestational psittacosis resulting in neonatal death identified by next-generation rna sequencing of postmortem, formalin-fixed lung tissue
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105100/
https://www.ncbi.nlm.nih.gov/pubmed/30151406
http://dx.doi.org/10.1093/ofid/ofy172
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