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Homologue-specific chromosome sequencing characterizes translocation junctions and permits allelic assignment

Chromosome translocations can be detected by cytogenetic analysis, but it is hard to characterize the breakpoints at the sequence level. Chromosome sorting by flow cytometry produces flow karyotypes that enable the isolation of abnormal chromosomes and the generation of chromosome-specific DNA. In t...

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Detalles Bibliográficos
Autores principales:	Kasai, Fumio, Pereira, Jorge C, Kohara, Arihiro, Ferguson-Smith, Malcolm A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105103/ https://www.ncbi.nlm.nih.gov/pubmed/29518182 http://dx.doi.org/10.1093/dnares/dsy007

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