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Reliable calibration by nonlinear standard addition method in the presence of additive interference effects

ABSTRACT: The possibility of adapting the Standard Addition Method (SAM) to calibration in very difficult analytical conditions, namely when there is a need to determine an analyte with the use of nonlinear calibration graph and in the presence of matrix components causing additive interference effe...

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Autores principales: Wieczorek, Marcin, Dębosz, Marek, Świt, Paweł, Piech, Aleksandra, Kasperek, Joanna, Kościelniak, Paweł
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105202/
https://www.ncbi.nlm.nih.gov/pubmed/30174345
http://dx.doi.org/10.1007/s00706-018-2203-1
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author Wieczorek, Marcin
Dębosz, Marek
Świt, Paweł
Piech, Aleksandra
Kasperek, Joanna
Kościelniak, Paweł
author_facet Wieczorek, Marcin
Dębosz, Marek
Świt, Paweł
Piech, Aleksandra
Kasperek, Joanna
Kościelniak, Paweł
author_sort Wieczorek, Marcin
collection PubMed
description ABSTRACT: The possibility of adapting the Standard Addition Method (SAM) to calibration in very difficult analytical conditions, namely when there is a need to determine an analyte with the use of nonlinear calibration graph and in the presence of matrix components causing additive interference effect, is investigated. To this aim the SAM in the common version and the Chemical H-point Standard Addition Method (C-HPSAM) realized by the flow injection technique were applied. Specifically, a flow manifold was used for construction of a set of nonlinear calibration graphs in different chemical conditions. As the graphs were intersected indicating both the additive interference effect and the analytical result free of this effect, the analyte concentration in the sample was able to be obtained with improved accuracy. The applicability of this approach was verified on the example of spectrophotometric determination of paracetamol in pharmaceuticals and of total acidity in wines. The C-HPSAM method enabled complete compensation of the additive effect and obtaining analytical results at a relative error not exceeding 6.0%. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-61052022018-08-30 Reliable calibration by nonlinear standard addition method in the presence of additive interference effects Wieczorek, Marcin Dębosz, Marek Świt, Paweł Piech, Aleksandra Kasperek, Joanna Kościelniak, Paweł Monatsh Chem Original Paper ABSTRACT: The possibility of adapting the Standard Addition Method (SAM) to calibration in very difficult analytical conditions, namely when there is a need to determine an analyte with the use of nonlinear calibration graph and in the presence of matrix components causing additive interference effect, is investigated. To this aim the SAM in the common version and the Chemical H-point Standard Addition Method (C-HPSAM) realized by the flow injection technique were applied. Specifically, a flow manifold was used for construction of a set of nonlinear calibration graphs in different chemical conditions. As the graphs were intersected indicating both the additive interference effect and the analytical result free of this effect, the analyte concentration in the sample was able to be obtained with improved accuracy. The applicability of this approach was verified on the example of spectrophotometric determination of paracetamol in pharmaceuticals and of total acidity in wines. The C-HPSAM method enabled complete compensation of the additive effect and obtaining analytical results at a relative error not exceeding 6.0%. GRAPHICAL ABSTRACT: [Image: see text] Springer Vienna 2018-08-07 2018 /pmc/articles/PMC6105202/ /pubmed/30174345 http://dx.doi.org/10.1007/s00706-018-2203-1 Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Original Paper
Wieczorek, Marcin
Dębosz, Marek
Świt, Paweł
Piech, Aleksandra
Kasperek, Joanna
Kościelniak, Paweł
Reliable calibration by nonlinear standard addition method in the presence of additive interference effects
title Reliable calibration by nonlinear standard addition method in the presence of additive interference effects
title_full Reliable calibration by nonlinear standard addition method in the presence of additive interference effects
title_fullStr Reliable calibration by nonlinear standard addition method in the presence of additive interference effects
title_full_unstemmed Reliable calibration by nonlinear standard addition method in the presence of additive interference effects
title_short Reliable calibration by nonlinear standard addition method in the presence of additive interference effects
title_sort reliable calibration by nonlinear standard addition method in the presence of additive interference effects
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105202/
https://www.ncbi.nlm.nih.gov/pubmed/30174345
http://dx.doi.org/10.1007/s00706-018-2203-1
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