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An ultraweak interaction in the intrinsically disordered replication machinery is essential for measles virus function
Measles virus genome encapsidation is essential for viral replication and is controlled by the intrinsically disordered phosphoprotein (P) maintaining the nucleoprotein in a monomeric form (N) before nucleocapsid assembly. All paramyxoviruses harbor highly disordered amino-terminal domains (P(NTD))...
Autores principales: | Milles, Sigrid, Jensen, Malene Ringkjøbing, Lazert, Carine, Guseva, Serafima, Ivashchenko, Stefaniia, Communie, Guillaume, Maurin, Damien, Gerlier, Denis, Ruigrok, Rob W. H., Blackledge, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105297/ https://www.ncbi.nlm.nih.gov/pubmed/30140745 http://dx.doi.org/10.1126/sciadv.aat7778 |
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