Regulated nuclear accumulation of a histone methyltransferase times the onset of heterochromatin formation in C. elegans embryos

Heterochromatin formation during early embryogenesis is timed precisely, but how this process is regulated remains elusive. We report the discovery of a histone methyltransferase complex whose nuclear accumulation and activation establish the onset of heterochromatin formation in Caenorhabditis eleg...

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Detalles Bibliográficos
Autores principales: Mutlu, Beste, Chen, Huei-Mei, Moresco, James J., Orelo, Barbara D., Yang, Bing, Gaspar, John M., Keppler-Ross, Sabine, Yates, John R., Hall, David H., Maine, Eleanor M., Mango, Susan E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105299/
https://www.ncbi.nlm.nih.gov/pubmed/30140741
http://dx.doi.org/10.1126/sciadv.aat6224

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