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Ndr kinases regulate retinal interneuron proliferation and homeostasis

Ndr2/Stk38l encodes a protein kinase associated with the Hippo tumor suppressor pathway and is mutated in a naturally-occurring canine early retinal degeneration (erd). To elucidate the retinal functions of Ndr2 and its paralog Ndr1/Stk38, we generated Ndr1 and Ndr2 single knockout mice. Although re...

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Detalles Bibliográficos
Autores principales:	Léger, Hélène, Santana, Evelyn, Leu, N. Adrian, Smith, Eliot T., Beltran, William A., Aguirre, Gustavo D., Luca, Francis C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105603/ https://www.ncbi.nlm.nih.gov/pubmed/30135513 http://dx.doi.org/10.1038/s41598-018-30492-9

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