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Early cellular innate immune responses drive Zika viral persistence and tissue tropism in pigtail macaques

The immunological and virological events that contribute to the establishment of Zika virus (ZIKV) infection in humans are unclear. Here, we show that robust cellular innate immune responses arising early in the blood and tissues in response to ZIKV infection are significantly stronger in males and...

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Detalles Bibliográficos
Autores principales: O’Connor, Megan A., Tisoncik-Go, Jennifer, Lewis, Thomas B., Miller, Charlene J., Bratt, Debra, Moats, Cassie R., Edlefsen, Paul T., Smedley, Jeremy, Klatt, Nichole R., Gale, Michael, Fuller, Deborah Heydenburg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105614/
https://www.ncbi.nlm.nih.gov/pubmed/30135445
http://dx.doi.org/10.1038/s41467-018-05826-w

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