Astrocyte-specific overexpression of Nrf2 protects against optic tract damage and behavioural alterations in a mouse model of cerebral hypoperfusion

Mouse models have shown that cerebral hypoperfusion causes white matter disruption and memory impairment relevant to the study of vascular cognitive impairment and dementia. The associated mechanisms include inflammation and oxidative stress are proposed to drive disruption of myelinated axons withi...

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Detalles Bibliográficos
Autores principales: Sigfridsson, Emma, Marangoni, Martina, Johnson, Jeffrey A., Hardingham, Giles E., Fowler, Jill H., Horsburgh, Karen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105641/
https://www.ncbi.nlm.nih.gov/pubmed/30135571
http://dx.doi.org/10.1038/s41598-018-30675-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105641/
https://www.ncbi.nlm.nih.gov/pubmed/30135571
http://dx.doi.org/10.1038/s41598-018-30675-4

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