KLF6 and STAT3 co-occupy regulatory DNA and functionally synergize to promote axon growth in CNS neurons

The failure of axon regeneration in the CNS limits recovery from damage and disease. Members of the KLF family of transcription factors can exert both positive and negative effects on axon regeneration, but the underlying mechanisms are unclear. Here we show that forced expression of KLF6 promotes a...

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Detalles Bibliográficos
Autores principales: Wang, Zimei, Mehra, Vatsal, Simpson, Matthew T., Maunze, Brian, Chakraborty, Advaita, Holan, Lyndsey, Eastwood, Erik, Blackmore, Murray G., Venkatesh, Ishwariya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105645/
https://www.ncbi.nlm.nih.gov/pubmed/30135567
http://dx.doi.org/10.1038/s41598-018-31101-5

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