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Transforming Growth Factor Beta Signaling in Dendritic Cells Is Required for Immunotolerance to Sperm in the Epididymis

The epididymis exhibits a less restrictive physical blood–tissue barrier than the testis and, while numerous immunosuppressive factors have been identified in the latter, no mechanisms for epididymal immunotolerance have been identified to date. Therefore, data are currently insufficient to explain...

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Detalles Bibliográficos
Autores principales: Pierucci-Alves, Fernando, Midura-Kiela, Monica T., Fleming, Sherry D., Schultz, Bruce D., Kiela, Pawel R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105693/
https://www.ncbi.nlm.nih.gov/pubmed/30166986
http://dx.doi.org/10.3389/fimmu.2018.01882