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The Biological Influence and Clinical Relevance of Polymorphism Within the NKG2D Ligands
NKG2D is a major regulator of the activity of cytotoxic cells and interacts with eight different ligands (NKG2DL) from two families of MIC and ULBP proteins. The selective forces that drove evolution of NKG2DL are uncertain, but are likely to have been dominated by infectious disease and cancer. Of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105697/ https://www.ncbi.nlm.nih.gov/pubmed/30166984 http://dx.doi.org/10.3389/fimmu.2018.01820 |