Synergetic improvements of sensitivity and specificity of nanowire field effect transistor gene chip by designing neutralized DNA as probe

Neutral DNA analogs as probes for the detection of target oligomers on the biosensors based on the field-effect transistor (FET) configuration feature advantages in the enhancement of sensitivity and signal-to-noise ratio. Herein, we used phosphate-methylated nucleotides to synthesize two partially...

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Detalles Bibliográficos
Autores principales: Hu, Wen-Pin, Tsai, Chih-Chin, Yang, Yuh-Shyong, Chan, Hardy Wai-Hong, Chen, Wen-Yih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105729/
https://www.ncbi.nlm.nih.gov/pubmed/30135473
http://dx.doi.org/10.1038/s41598-018-30996-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105729/
https://www.ncbi.nlm.nih.gov/pubmed/30135473
http://dx.doi.org/10.1038/s41598-018-30996-4

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