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Synergetic improvements of sensitivity and specificity of nanowire field effect transistor gene chip by designing neutralized DNA as probe
Neutral DNA analogs as probes for the detection of target oligomers on the biosensors based on the field-effect transistor (FET) configuration feature advantages in the enhancement of sensitivity and signal-to-noise ratio. Herein, we used phosphate-methylated nucleotides to synthesize two partially...
Autores principales: | Hu, Wen-Pin, Tsai, Chih-Chin, Yang, Yuh-Shyong, Chan, Hardy Wai-Hong, Chen, Wen-Yih |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105729/ https://www.ncbi.nlm.nih.gov/pubmed/30135473 http://dx.doi.org/10.1038/s41598-018-30996-4 |
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