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Application of auxin-inducible degron technology to mouse oocyte activation with PLCζ

In mammals, spermatozoa activate oocytes by triggering a series of intracellular Ca(2+) oscillations with phospholipase C zeta (PLCζ), a sperm-borne oocyte-activating factor. Because the introduction of PLCζ alone can induce oocyte activation, it might be a promising reagent for assisted reproductiv...

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Detalles Bibliográficos
Autores principales: MIURA, Kento, MATOBA, Shogo, OGONUKI, Narumi, NAMIKI, Takafumi, ITO, Junya, KASHIWAZAKI, Naomi, OGURA, Atsuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105737/
https://www.ncbi.nlm.nih.gov/pubmed/29731504
http://dx.doi.org/10.1262/jrd.2018-053