The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options

This case reports cryptococcal meningitis in an HIV positive woman on antiretroviral therapy, presenting with left middle cerebral artery stroke at 30 weeks gestation. The patient had well-controlled HIV (CD4 count over 200 cells/mL). The immunosuppressive effects of the pregnancy likely contributed...

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Autores principales: Bright, Philip D., Lupiya, Duncan, van Oosterhout, Joep J., Chen, Amy, Harrison, Thomas S., Chan, Adrienne K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105915/
https://www.ncbi.nlm.nih.gov/pubmed/30148053
http://dx.doi.org/10.1016/j.mmcr.2017.10.002
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author Bright, Philip D.
Lupiya, Duncan
van Oosterhout, Joep J.
Chen, Amy
Harrison, Thomas S.
Chan, Adrienne K.
author_facet Bright, Philip D.
Lupiya, Duncan
van Oosterhout, Joep J.
Chen, Amy
Harrison, Thomas S.
Chan, Adrienne K.
author_sort Bright, Philip D.
collection PubMed
description This case reports cryptococcal meningitis in an HIV positive woman on antiretroviral therapy, presenting with left middle cerebral artery stroke at 30 weeks gestation. The patient had well-controlled HIV (CD4 count over 200 cells/mL). The immunosuppressive effects of the pregnancy likely contributed to the development of cryptococcal disease. The patient was successfully treated with two weeks of amphotericin B followed by fluconazole, delivered a healthy baby, but remained with a permanent severe neurological deficit.
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spelling pubmed-61059152018-08-24 The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options Bright, Philip D. Lupiya, Duncan van Oosterhout, Joep J. Chen, Amy Harrison, Thomas S. Chan, Adrienne K. Med Mycol Case Rep Case Report This case reports cryptococcal meningitis in an HIV positive woman on antiretroviral therapy, presenting with left middle cerebral artery stroke at 30 weeks gestation. The patient had well-controlled HIV (CD4 count over 200 cells/mL). The immunosuppressive effects of the pregnancy likely contributed to the development of cryptococcal disease. The patient was successfully treated with two weeks of amphotericin B followed by fluconazole, delivered a healthy baby, but remained with a permanent severe neurological deficit. Elsevier 2017-10-28 /pmc/articles/PMC6105915/ /pubmed/30148053 http://dx.doi.org/10.1016/j.mmcr.2017.10.002 Text en © 2017 The Authors http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Bright, Philip D.
Lupiya, Duncan
van Oosterhout, Joep J.
Chen, Amy
Harrison, Thomas S.
Chan, Adrienne K.
The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options
title The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options
title_full The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options
title_fullStr The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options
title_full_unstemmed The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options
title_short The treatment of a pregnant HIV positive patient with cryptococcal meningitis in Malawi. Case report and review of treatment options
title_sort treatment of a pregnant hiv positive patient with cryptococcal meningitis in malawi. case report and review of treatment options
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6105915/
https://www.ncbi.nlm.nih.gov/pubmed/30148053
http://dx.doi.org/10.1016/j.mmcr.2017.10.002
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