High-Throughput Screening Identifies Genes Required for Candida albicans Induction of Macrophage Pyroptosis

The innate immune system is the first line of defense against invasive fungal infections. As a consequence, many successful fungal pathogens have evolved elegant strategies to interact with host immune cells. For example, Candida albicans undergoes a morphogenetic switch coupled to cell wall remodel...

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Detalles Bibliográficos
Autores principales: O’Meara, Teresa R., Duah, Kwamaa, Guo, Cynthia X., Maxson, Michelle E., Gaudet, Ryan G., Koselny, Kristy, Wellington, Melanie, Powers, Michael E., MacAlpine, Jessie, O’Meara, Matthew J., Veri, Amanda O., Grinstein, Sergio, Noble, Suzanne M., Krysan, Damian, Gray-Owen, Scott D., Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106084/
https://www.ncbi.nlm.nih.gov/pubmed/30131363
http://dx.doi.org/10.1128/mBio.01581-18

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