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Hyperactive ryanodine receptors in human heart failure and ischaemic cardiomyopathy reside outside of couplons

AIMS: In ventricular myocytes from humans and large mammals, the transverse and axial tubular system (TATS) network is less extensive than in rodents with consequently a greater proportion of ryanodine receptors (RyRs) not coupled to this membrane system. TATS remodelling in heart failure (HF) and a...

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Detalles Bibliográficos
Autores principales:	Dries, Eef, Santiago, Demetrio J, Gilbert, Guillaume, Lenaerts, Ilse, Vandenberk, Bert, Nagaraju, Chandan K, Johnson, Daniel M, Holemans, Patricia, Roderick, H Llewelyn, Macquaide, Niall, Claus, Piet, Sipido, Karin R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106102/ https://www.ncbi.nlm.nih.gov/pubmed/29668881 http://dx.doi.org/10.1093/cvr/cvy088

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