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Notch-1 Signaling Activation and Progesterone Receptor Expression in Ectopic Lesions of Women With Endometriosis

CONTEXT: Progesterone (P) resistance is a hallmark of endometriosis, but the underlying mechanism(s) for loss of P sensitivity leading to lesion establishment remains poorly understood. OBJECTIVE: To evaluate the association between Notch-1 signaling activation and P resistance in the progression of...

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Detalles Bibliográficos
Autores principales: Brown, Dustin M, Lee, Hsiu-Chi, Liu, Shi, Quick, Charles M, Fernandes, Lorenzo M, Simmen, Frank A, Tsai, Shaw-Jenq, Simmen, Rosalia C M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106104/
https://www.ncbi.nlm.nih.gov/pubmed/30151432
http://dx.doi.org/10.1210/js.2018-00007