Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide

AIMS: Monocytes play an important role in hypertension. Circulating monocytes in humans exist as classical, intermediate, and non-classical forms. Monocyte differentiation can be influenced by the endothelium, which in turn is activated in hypertension by mechanical stretch. We sought to examine the...

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Detalles Bibliográficos
Autores principales: Loperena, Roxana, Van Beusecum, Justin P, Itani, Hana A, Engel, Noah, Laroumanie, Fanny, Xiao, Liang, Elijovich, Fernando, Laffer, Cheryl L, Gnecco, Juan S, Noonan, Jonathan, Maffia, Pasquale, Jasiewicz-Honkisz, Barbara, Czesnikiewicz-Guzik, Marta, Mikolajczyk, Tomasz, Sliwa, Tomasz, Dikalov, Sergey, Weyand, Cornelia M, Guzik, Tomasz J, Harrison, David G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106108/
https://www.ncbi.nlm.nih.gov/pubmed/29800237
http://dx.doi.org/10.1093/cvr/cvy112

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