Fluconazole-Resistant Candida parapsilosis Bloodstream Isolates with Y132F Mutation in ERG11 Gene, South Korea

We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hosp...

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Autores principales: Choi, Yong Jun, Kim, Yae-Jean, Yong, Dongeun, Byun, Jung-Hyun, Kim, Taek Soo, Chang, Yun Sil, Choi, Min Ji, Byeon, Seung Ah, Won, Eun Jeong, Kim, Soo Hyun, Shin, Myung Geun, Shin, Jong Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2018
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106402/
https://www.ncbi.nlm.nih.gov/pubmed/30124412
http://dx.doi.org/10.3201/eid2409.180625
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author Choi, Yong Jun
Kim, Yae-Jean
Yong, Dongeun
Byun, Jung-Hyun
Kim, Taek Soo
Chang, Yun Sil
Choi, Min Ji
Byeon, Seung Ah
Won, Eun Jeong
Kim, Soo Hyun
Shin, Myung Geun
Shin, Jong Hee
author_facet Choi, Yong Jun
Kim, Yae-Jean
Yong, Dongeun
Byun, Jung-Hyun
Kim, Taek Soo
Chang, Yun Sil
Choi, Min Ji
Byeon, Seung Ah
Won, Eun Jeong
Kim, Soo Hyun
Shin, Myung Geun
Shin, Jong Hee
author_sort Choi, Yong Jun
collection PubMed
description We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing.
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spelling pubmed-61064022018-09-01 Fluconazole-Resistant Candida parapsilosis Bloodstream Isolates with Y132F Mutation in ERG11 Gene, South Korea Choi, Yong Jun Kim, Yae-Jean Yong, Dongeun Byun, Jung-Hyun Kim, Taek Soo Chang, Yun Sil Choi, Min Ji Byeon, Seung Ah Won, Eun Jeong Kim, Soo Hyun Shin, Myung Geun Shin, Jong Hee Emerg Infect Dis Research Letter We recently observed the emergence of fluconazole-resistant Candida parapsilosis bloodstream isolates harboring a Y132F substitution in Erg11p in South Korea. These Y132F isolates had a higher propensity to cause clonal transmission than other fluconazole-resistant isolates and persisted within hospitals for several years, as revealed by microsatellite typing. Centers for Disease Control and Prevention 2018-09 /pmc/articles/PMC6106402/ /pubmed/30124412 http://dx.doi.org/10.3201/eid2409.180625 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research Letter
Choi, Yong Jun
Kim, Yae-Jean
Yong, Dongeun
Byun, Jung-Hyun
Kim, Taek Soo
Chang, Yun Sil
Choi, Min Ji
Byeon, Seung Ah
Won, Eun Jeong
Kim, Soo Hyun
Shin, Myung Geun
Shin, Jong Hee
Fluconazole-Resistant Candida parapsilosis Bloodstream Isolates with Y132F Mutation in ERG11 Gene, South Korea
title Fluconazole-Resistant Candida parapsilosis Bloodstream Isolates with Y132F Mutation in ERG11 Gene, South Korea
title_full Fluconazole-Resistant Candida parapsilosis Bloodstream Isolates with Y132F Mutation in ERG11 Gene, South Korea
title_fullStr Fluconazole-Resistant Candida parapsilosis Bloodstream Isolates with Y132F Mutation in ERG11 Gene, South Korea
title_full_unstemmed Fluconazole-Resistant Candida parapsilosis Bloodstream Isolates with Y132F Mutation in ERG11 Gene, South Korea
title_short Fluconazole-Resistant Candida parapsilosis Bloodstream Isolates with Y132F Mutation in ERG11 Gene, South Korea
title_sort fluconazole-resistant candida parapsilosis bloodstream isolates with y132f mutation in erg11 gene, south korea
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106402/
https://www.ncbi.nlm.nih.gov/pubmed/30124412
http://dx.doi.org/10.3201/eid2409.180625
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