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Scanning electron microscopy of granuloma annulare

Light microscopy of granuloma annulare shows mucin deposition with lympho-histiocytic infiltrate. We describe the ultrastructural three-dimensional aspects of a typical case of granuloma with characteristic histopathological findings. At the ultrastructural level, affected collagen bundles and granu...

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Detalles Bibliográficos
Autores principales: de Almeida Jr., Hiram Larangeira, Bicca, Eduardo de Barros Coelho, de Andrade, Mariani Magnus, Andrade Neto, Pedro da Rocha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106657/
https://www.ncbi.nlm.nih.gov/pubmed/30156630
http://dx.doi.org/10.1590/abd1806-4841.20187409
Descripción
Sumario:Light microscopy of granuloma annulare shows mucin deposition with lympho-histiocytic infiltrate. We describe the ultrastructural three-dimensional aspects of a typical case of granuloma with characteristic histopathological findings. At the ultrastructural level, affected collagen bundles and granular mucin deposition were observed. Round cells corresponding to lymphocytes were identified. Bigger oval cells, corresponding to isolated or palisading histiocytes were also found. The ultrastructural aspects overlap with light microscopy and contribute to its iconographic documentation.