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Verrucous hemangioma and histopathological differential diagnosis with angiokeratoma circumscriptum neviforme

Verrucous hemangioma is a rare vascular skin disorder with an immune profile similar to vascular neoplasms, but with behavior and evolution of vascular malformations. Its main differential diagnosis is angiokeratoma circumscriptum neviforme, with an almost indistinguishable clinical presentation bec...

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Autores principales: Oppermann, Kenselyn, Boff, Ana Letícia, Bonamigo, Renan Rangel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Dermatologia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106676/
https://www.ncbi.nlm.nih.gov/pubmed/30156622
http://dx.doi.org/10.1590/abd1806-4841.20187259
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author Oppermann, Kenselyn
Boff, Ana Letícia
Bonamigo, Renan Rangel
author_facet Oppermann, Kenselyn
Boff, Ana Letícia
Bonamigo, Renan Rangel
author_sort Oppermann, Kenselyn
collection PubMed
description Verrucous hemangioma is a rare vascular skin disorder with an immune profile similar to vascular neoplasms, but with behavior and evolution of vascular malformations. Its main differential diagnosis is angiokeratoma circumscriptum neviforme, with an almost indistinguishable clinical presentation because both diseases appear as erythematous patches that evolve to violaceous plaques, becoming scaly and even verrucous, most commonly affecting the lower limbs. Histopathology is crucial for the correct diagnosis: while in angiokeratoma the vascular alterations are limited to the papillary dermis, verrucous hemangioma extends deep into the dermis, reaching the subcutaneous tissue.
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spelling pubmed-61066762018-09-01 Verrucous hemangioma and histopathological differential diagnosis with angiokeratoma circumscriptum neviforme Oppermann, Kenselyn Boff, Ana Letícia Bonamigo, Renan Rangel An Bras Dermatol Dermatopathology Verrucous hemangioma is a rare vascular skin disorder with an immune profile similar to vascular neoplasms, but with behavior and evolution of vascular malformations. Its main differential diagnosis is angiokeratoma circumscriptum neviforme, with an almost indistinguishable clinical presentation because both diseases appear as erythematous patches that evolve to violaceous plaques, becoming scaly and even verrucous, most commonly affecting the lower limbs. Histopathology is crucial for the correct diagnosis: while in angiokeratoma the vascular alterations are limited to the papillary dermis, verrucous hemangioma extends deep into the dermis, reaching the subcutaneous tissue. Sociedade Brasileira de Dermatologia 2018 /pmc/articles/PMC6106676/ /pubmed/30156622 http://dx.doi.org/10.1590/abd1806-4841.20187259 Text en http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivative License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium provided the original work is properly cited and the work is not changed in any way.
spellingShingle Dermatopathology
Oppermann, Kenselyn
Boff, Ana Letícia
Bonamigo, Renan Rangel
Verrucous hemangioma and histopathological differential diagnosis with angiokeratoma circumscriptum neviforme
title Verrucous hemangioma and histopathological differential diagnosis with angiokeratoma circumscriptum neviforme
title_full Verrucous hemangioma and histopathological differential diagnosis with angiokeratoma circumscriptum neviforme
title_fullStr Verrucous hemangioma and histopathological differential diagnosis with angiokeratoma circumscriptum neviforme
title_full_unstemmed Verrucous hemangioma and histopathological differential diagnosis with angiokeratoma circumscriptum neviforme
title_short Verrucous hemangioma and histopathological differential diagnosis with angiokeratoma circumscriptum neviforme
title_sort verrucous hemangioma and histopathological differential diagnosis with angiokeratoma circumscriptum neviforme
topic Dermatopathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106676/
https://www.ncbi.nlm.nih.gov/pubmed/30156622
http://dx.doi.org/10.1590/abd1806-4841.20187259
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