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Cholesterol secosterol aldehyde adduction and aggregation of Cu,Zn-superoxide dismutase: Potential implications in ALS
Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by degeneration of upper and lower motor neurons. While the fundamental causes of the disease are still unclear, the accumulation of Cu,Zn-superoxide dismutase (SOD1) immunoreactive aggregates is associated with famili...
Autores principales: | Dantas, Lucas S., Chaves-Filho, Adriano B., Coelho, Fernando R., Genaro-Mattos, Thiago C., Tallman, Keri A., Porter, Ned A., Augusto, Ohara, Miyamoto, Sayuri |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106709/ https://www.ncbi.nlm.nih.gov/pubmed/30142602 http://dx.doi.org/10.1016/j.redox.2018.08.007 |
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