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Cholesterol secosterol aldehyde adduction and aggregation of Cu,Zn-superoxide dismutase: Potential implications in ALS

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by degeneration of upper and lower motor neurons. While the fundamental causes of the disease are still unclear, the accumulation of Cu,Zn-superoxide dismutase (SOD1) immunoreactive aggregates is associated with famili...

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Detalles Bibliográficos
Autores principales: Dantas, Lucas S., Chaves-Filho, Adriano B., Coelho, Fernando R., Genaro-Mattos, Thiago C., Tallman, Keri A., Porter, Ned A., Augusto, Ohara, Miyamoto, Sayuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106709/
https://www.ncbi.nlm.nih.gov/pubmed/30142602
http://dx.doi.org/10.1016/j.redox.2018.08.007

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