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Comprehensive Assessment of Degradation Behavior of Simvastatin by UHPLC/MS Method, Employing Experimental Design Methodology

This manuscript describes comprehensive approach for assessment of degradation behavior of simvastatin employing experimental design methodology as scientific multifactorial strategy. Experimental design methodology was used for sample preparation and UHPLC method development and optimization. Simva...

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Detalles Bibliográficos
Autores principales: Hadzieva Gigovska, Maja, Petkovska, Ana, Acevska, Jelena, Nakov, Natalija, Antovska, Packa, Ugarkovic, Sonja, Dimitrovska, Aneta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106721/
https://www.ncbi.nlm.nih.gov/pubmed/30174695
http://dx.doi.org/10.1155/2018/7170539