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Models of cell signaling uncover molecular mechanisms of high-risk neuroblastoma and predict disease outcome
BACKGROUND: Despite the progress in neuroblastoma therapies the mortality of high-risk patients is still high (40–50%) and the molecular basis of the disease remains poorly known. Recently, a mathematical model was used to demonstrate that the network regulating stress signaling by the c-Jun N-termi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106876/ https://www.ncbi.nlm.nih.gov/pubmed/30134948 http://dx.doi.org/10.1186/s13062-018-0219-4 |