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Identification of early biological changes in palmitate-treated isolated human islets

BACKGROUND: Long-term exposure to elevated levels of free fatty acids (FFAs) is deleterious for beta-cell function and may contribute to development of type 2 diabetes mellitus (T2DM). Whereas mechanisms of impaired glucose-stimulated insulin secretion (GSIS) in FFA-treated beta-cells have been inte...

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Detalles Bibliográficos
Autores principales:	Sargsyan, Ernest, Cen, Jing, Roomp, Kirsten, Schneider, Reinhard, Bergsten, Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106933/ https://www.ncbi.nlm.nih.gov/pubmed/30134843 http://dx.doi.org/10.1186/s12864-018-5008-z

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