Divergent Allele Advantage at Human MHC Genes: Signatures of Past and Ongoing Selection

The highly polymorphic genes of the major histocompatibility complex (MHC) play a key role in adaptive immunity. Divergent allele advantage, a mechanism of balancing selection, is proposed to contribute to their exceptional polymorphism. It assumes that MHC genotypes with more divergent alleles allo...

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Detalles Bibliográficos
Autores principales: Pierini, Federica, Lenz, Tobias L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Discoveries
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106954/
https://www.ncbi.nlm.nih.gov/pubmed/29893875
http://dx.doi.org/10.1093/molbev/msy116

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6106954/
https://www.ncbi.nlm.nih.gov/pubmed/29893875
http://dx.doi.org/10.1093/molbev/msy116

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